Written by Slawomir (“Swavak”) Gromadzki, MPH


Due to the severe soil depletion, poor dietary habits, use of popular stimulants, and chronic stress millions suffer from magnesium deficiency without even knowing it. It is estimated that 80% of us are deficient in magnesium. In addition, magnesium deficiency is often misdiagnosed because it does not show up in blood tests as only 1% of the body’s magnesium is stored in the blood. According to Dr. Norman Shealy, “Every known illness is associated with a magnesium deficiency. Magnesium deficiency may be responsible for more diseases than any other nutrient.”


Magnesium is an essential mineral that contributes to normal muscle, brain and nervous system function, maintenance of healthy bones & teeth, reduction of tiredness & fatigue, normal energy yielding metabolism, electrolyte balance, and protein synthesis. Magnesium is important to support a healthy immune system and cardiovascular function. Due to its ability to relax muscles magnesium supplements can be highly beneficial for people who suffer from muscle cramps including those with spastic colon, stomach cramps, migraine headaches, and women with excessive uterine contractions. In human body magnesium is necessary to activate all the enzymes that convert vitamin D into its final form. In people who are deficient in magnesium vitamin D supplementation brings no benefits even if very high doses of vitamin D are taken over a long period of time.


Magnesium Bisglycinate utilizes magnesium bound to the amino acid glycine, which facilitates intestinal absorption of magnesium. It may have better relaxing effect than other forms because it is bound to amino acid glycine known for its calming impact on the nervous system. Some experts claim that Magnesium Bisglycinate chelate appears to be the safest and most absorbable form of magnesium. Magnesium Bisglycinate, is not only a very well absorbed form of magnesium, but also doesn’t impose a laxative effect. For this reason, it is more suitable for people with inflamed and oversensitive lining of the colon which still needs magnesium but not the laxative one. At the same time Magnesium Bisglycinate may help relief constipation by helping increase production of the relaxing and calming hormone Serotonin known to regulate intestinal motility.


There are many magnesium bisglycinate products, which often consist of a none-reactive and not chelated blend of magnesium compound and l-glycine. You need to make sure you choose Magnesium Bisglycinate which is in a 100% pure chelated and fully reactive form as it is believed that this form is, on average, ten times more absorbable than standard magnesium.

It is very important to know that not all magnesium bisglycinate supplements are the same as many of them contain only cheap magnesium, such as oxide, mixed with glycine. These two ingredients are not chemically bound but only mixed in a capsule or tablet hoping that in the GI tract this mixture will eventually make magnesium glycinate. Those who practice it maintain that it has been done to increase the bioavailability, but in reality it results in a much lower absorption.


Good chelated Magnesium Bisglycinate should be fortified with Vitamin B6 which facilitates cellular uptake of magnesium, increases its effectiveness and limits excretion. It was found that supplemental magnesium combined with Vitamin B6 was more effective than magnesium alone.

Apart from improving the absorption and effectiveness of magnesium, Vitamin B6 contributes to normal function of the nervous & immune system, normal psychological function, regulation of hormonal balance and hormonal activity in both men and women, and reduction of tiredness & fatigue.


  • Helps impose a calming effect on the nervous system
  • Taken before bedtime benefits people with sleep problems
  • Helps impose relaxing effects on muscles and internal organs
  • Recommended for people with stomach cramps and spastic colon
  • Beneficial for women experiencing premenstrual syndrome (PMS) & uterine cramps
  • Supports heart muscle function, relaxation of blood vessels & normal blood pressure
  • Helps maintain functionality of the immune system
  • Contributes to the energy production and healthy metabolism
  • Supports development and health of bones and teeth
  • Absolutely crucial  for proper conversion and effectiveness of supplemental Vitamin D
  • Helps maintain healthy blood glucose levels
  • Supports production of the good mood hormone, Serotonin
  • May easy migraine headaches (works even better when combined with Vitamin B2 & 5-HTP Tryptophan)
  • Helps increase ability to control stress
  • May help relief constipation






Any information or product suggested on this website is not intended to diagnose, treat, cure or prevent any medical condition. Never disregard medical advice or delay in seeking it because of something you have read on this website. Consult your primary healthcare physician before using any supplements or making any changes to your regime.